Electrospinning nanofiber application of nano instant mask and expansion

Views: 64 Author: Site Editor Publish Time: 2024-10-19 Origin: Site

Instant skin care mask application process

instant skincare mask application process

Q1:Why is it called a skin mask?

Q2:The difference between freeze-dried masks?


Background information

Skin care concept development history

As of May 2023, the number of discussions about precision skin care on the Tiktok platform has reached 18 million +, an increase of more than 27% over 2022; The number of precision skin care notes of XiaoHongbook platform reached 50,000 +, an increase of more than 25% over 2022, which indicates that precision skin care is expected to continue to develop and become a potential track for the skin care industry.

Before 2010: Basic skin care

2010-2020: Effective skin care

2020 to present: Precision skin care

Consumers value brands, skin care awareness in the basic care stage, weak knowledge of skin problems, attention to single function, focusing on cleansing, hydration and other needs.

Consumers value efficacy, skin care awareness has increased, pay attention to product ingredients, efficacy, "early C late A, oil skin" and other ingredients of skin care concept popular.

Consumers value the effect, from focusing on concentration to absorption, skin care refinement, scientific demand improvement, through the combination of skin care ingredients and beauty instruments, achieve accurate skin care.

Consumer demand and existing product pain points

Problems



  • The pursuit of strong efficacy, immediate results, ignoring product safety.

  • The focus is biased towards channels and traffic,  no innovation highlights.

  • The mask cloth is uneven and plagued by quality problems for a long time.

  • It is difficult for nutrients or functional substances to achieve deep penetration.







Technology features:

No corrosion, strong display force, high absorption, etc.


Increasing age: the loss of skin collagen accelerates, resulting in skin aging problems; 

Light pollution, ultraviolet light reflection in the reflective panel and artificial light damage the skin;

Air pollution: floating in the air of all kinds of heavy metal pollutants, chemical pollutants, such as industrial smoke can cause skin aging.

Increased pressure: high-intensity work, skin collagen loss accelerated, serious aging.

Technology introduction

Technical principle

Technical principle


microstructure

Electrospinning is a technology that uses high-voltage electrostatic force to stretch liquid materials with certain viscosity and surface tension into nanofibers, which can prepare multi-material and multi-structure fibers with diameters of 1nm-10μm. Suitable for a variety of polymer materials, with the characteristics of low cost and high efficiency, and is widely used in filtration and environmental protection, biomedicine, waterproof and breathable, national defense and other fields.

Nanofiber applications - Water soluble materials

Wound dressing

With large specific surface area, controllable porosity and good biological properties, it is beneficial to cell respiration, inhibit bacterial infection of wounds, promote cell proliferation and accelerate wound healing.

Wound dressing


Nano instant skin care mask

1)Good feeling: Good percutaneous drug release/cosmetic active ingredient characteristics.The beauty active ingredients are completely released at a certain rate, achieve the desired beauty effect.

(2)Fast absorption:As the carrier of drug delivery, nanofibers have a large specific surface area and porous structure, strong mutual permeability with other substances, which is very conducive to the diffusion and dissolution of drugs, improve the transdermal absorption. of drugs.

Nano instant skin care mask

Final product form: Dry instant film, transparent essential oil film.

Production technology process

production technology process

Most of the filament diameter of the nanofiber membrane is 300-600nm, easy to absorb the stratum corneum.

Nano instant efficacy membrane - Product features

Nano instant efficacy membrane - Product features

Feature 1: Burst release, promote penetration

Comparison of different osmotic promotion methods

Physical method

Chemical method

Nanofiber technology

  • Physical method

Common physical methods include iontophoresis, electroporation, ultrasonic osmosis, microneedle,etc.


Advantages: Promote the efficient absorption of substances.

Disadvantages: Cumbersome process; high price.


Used in clinical or medical beauty, less in cosmetics.

  • Chemical method

Chemopromoters enhance permeability by interacting with stratum corneum lipids to alter their arrangement.


Advantages: Promote efficient absorbing.

Disadvantages: Certain substances have side effects.


  • Nanofiber technology

The efficacy ingredients are transformed into stable nanostructures, which are more easily absorbed by the skin into the cortex and promote absorption.


Advantages: Simple process, low price, no side effects.


Nanofiber "Burst release" principle

Burst release: The active ingredient is "burst" released from the carrier for a short time.

The Higuchi model and Korsmeyer-Peppas kinetic model are used to analyze and demonstrate the principle of "burst release" of active ingredients from nanofibers.

Nanofiber Burst release principle


Experimental results show that the smaller the diameter of a single fiber, the larger the specific surface area, the more significant the "burst release" effect.

The active ingredient can be released from the electrostatic spinning PVA nanofiber matrix in 60s  (up to 100% caffeine)

Nanofiber features



Nanofibers from "burst release" to "rapid penetration"

Nanofibers from burst release to rapid penetration

Nanofiber skin care film advantages: Rapid penetration, deep penetration, easy to load power ingredients.

Penetration experiment proof

Penetration comparison of ibuprofen in electrospun membrane and non-woven fabric


Research from Tianjin University

Comparison of VA and VC penetration in electrospun film and non-woven fabric

A joint study by the National University of Singapore and Singapore Central Hospital





The results show that the nanofiber structure can significantly improve the transdermal absorption of active ingredients by 2-10 times!

Research from Tianjin University

A joint study by the National University of Singapore and Singapore Central Hospital

Authoritative test showed that: Nano fiber membrane permeability is daub using traditional way about four times that of nanometer fiber structure permeation enhancers.

Penetration experiment proof

Feature 2: Solid lock effect, no corrosion protection

Preservative-free, long-lasting storage

Preservative-free, long-lasting storage

  • Long-term preservation: Solid masks have a relatively long shelf life, helps maintain the stability and efficacy of the product.

  • Preservative-free: No moisture, easy to preserve, not easy to nourish bacteria, no need to add preservatives, alcohol and other additives.

  • Easy use: Solid masks usually do not drip or flow when applied, making them easier to grasp and reducing waste and inconvenience.

Solid lock effect advantage: High cost performance; can add effective ingredients that are easy to hydrolyze and difficult to penetrate; no corrosion protection.


Feature 3: Filling fine lines and tighten the skin




  • The texture structure of the nano mask is close to the skin texture, small scale, easy to wet the cuticle and fill into the micron level skin fine lines, the instant wrinkling effect is obvious.


  • Nanofibers have a microporous structure, high porosity, can be tightly fitted to the skin, can breathe and permeate moisture.

Filling fine lines


Advantages: Both long-term and short-term effects

Product application

Product application 1: One minute before makeup mask

Traditional makeup process:


The main purpose of morning skin care is to cleanse, hydrate, protect, and prepare the skin for daily makeup.

The basic steps of makeup include cleansing, moisturizing, primer, makeup, concealer, setting, eye makeup, blush and lipstick, process is tedious.

Evening skincare is a key time for skin repair and recovery, including makeup removal, cleansing, conditioning, hydration, repair and maintenance steps.

Traditional makeup process


Problems: Makeup process is cumbersome; card powder; trouble to remove makeup; skin contact with cosmetics can cause allergies.

Streamlined skin care: replace the skin care before makeup, 60 seconds to complete the use, saving time.

Streamlined skin care

Card powder savior: fill fine lines, smooth the skin; fast penetration, lock water and moisturize.

Card powder savior

Functional ingredients: silk protein, silk heart protein, Pullulan Polysaccharide, trehalose, sodium hyaluronate, plant polysaccharide, Asiaticoside, niacinamide, papain, Hydrolyzed collagen, oat beta glucose, maltodextrin, gelatin.

Makeup is not easy to card powder: take the non-card powder, good air permeability, moisture absorption, hold makeup for more than 8 hours.

Easy to remove makeup: instant skin care mask as a protective base makeup, no need to remove makeup water, just cleanser can remove makeup, no sebum damage.

Pre-makeup, skin care dual use: high penetration, ten seconds quick hydration, containing skin care ingredients, while completing hydration and skin care.

Efficacy evaluation report,Product patent

Use video

Use video.mp4


Application 2: Firming instant skin care mask

Features: Fill fine lines, strong wrinkle removal

Fill fine lines, strong wrinkle remova

Product feature:

Anti-aging firming: The release of active ingredients such as hyaluronic acid, polypeptides, hydroxy acid, etc. stimulates the production of collagen and elastin to help maintain the elasticity and firmness of the skin.

Filling fine lines: The nano mask is smaller, easier to wet the cuticle and fill into the micron level of skin fine lines, instant wrinkling effect is obvious.

High permeability: Nanometer microporous structure, high active ingredient content, easier penetration.

Instant skincare mask video .mp4

instant skincare mask application process

Skin fine lines: 20-50 microns; Nanofibers: 300-600 nm; Spray requirements: Less than fine lines

Expand product application 3: Jellyfish skin invisible application

Product features: transparent skin, elastic

Invisible moisturizing cold compress


Fatigue relief contact patch

Trackless sports sunscreen patch

Invisible moisturizing cold compress


  • Breathable and comfortable: The nano-porous breathable structure keeps the eye skin fresh and comfortable.

  • Long-lasting moisture: Microporous structure better load moisturizing ingredients.

Fatigue relief contact patch


  • Continuous relief: Slow release of active ingredients, continuous relief of fatigue.

  • Transparent skin patch: the eye patch does not fall off and is elastic, and does not delay normal communication.

Trackless sports sunscreen patch


  • Waterproof and sweat resistant: do not fall off during exercise.

  • Skin barrier: isolation of sunscreen ingredients, greatly reducing the damage to the skin.

  • Strong durability: It has good adhesion and reduces the trouble of frequent recoating.

Expand product application 4: Instant medicine patch

Sports trauma, joint pain, inflammation and swelling, skin diseases and other diseases have long plagued people's health, for this painful and chronic disease, the medical industry often uses drugs to apply, through local penetration, transdermal absorption to achieve the purpose of treatment or relief of symptoms. Commonly used medicines include medical ointments, sprays, patches and other forms.

Trauma, swelling and other common diseases

Commonly used for topical administration

Trauma, swelling and other common diseases

Commonly used for topical administration


Medical ointment

Nebula

Herbal patch

Medical ointment

Nebula

Herbal patch

  • Greasy texture: Greasy feeling is strong, affecting comfort and experience.

  • Poor permeability:Limited penetration, affecting drug absorption and efficacy.

  • Difficult dose control: Drug waste, difficult to control the precise dose.

  • Poor air permeability: Impermeable, causing moist and sultry skin.

  • Inconvenient to carry: Volume is large, affecting patients to carry.

  • Difficult dose control: Drug waste, difficult to accurately control the dose.

  • Environmental restrictions: Special environment, temperature and humidity and other effects.

  • Adverse reactions: Affected respiration, molecular diffusion inhalation.

  • Grease discomfort: greasy feeling is strong, affecting comfort and experience.

  • Sticky residue: strong viscosity, residue is difficult to remove after adhesion.

  • Poor air permeability: impermeable, causing moist and sultry skin.

  • Affect the appearance: apply to the affected area, exposing the patch affects the appearance of the outside.

Solution: A kind of medical adhesive with controllable dose, long acting and good penetration.

Product advantage:

  • Uniform drug loading: The drug is distributed quantitatively and evenly to avoid local overdose or insufficiency of the drug on the applied surface.

  • Drug sustained release:It can realize the continuous release of the drug, extend the duration of the drug effect, and reduce the frequent use of the drug.

  • Nano permeability promotion: Has a large specific surface area and porous structure, improve the drug transdermal absorption, make up for the intervention of non-pharmaceutical ingredients.

Expand product application 5: Medical tape/backing material

Product features: High skin adhesion (use foreign body feeling ≈0), waterproof, anti-sweat and moisture.

Technology: TPU + nanofibers membrane biological glue coating

Medical tape,backing material

Permeable microporous diffusion mechanism

Permeable microporous diffusion mechanism




  • Light fog: 20-200 microns

  • Fiber membrane pore size:   0.2~5 microns

  • Water vapor molecules: Diameter 0.0004 microns



Expand product applications

Expand product applications-

Equipment introduction

Machine


  • 20 years spinning technology accumulation, ensuring stable and continuous production; 

  • Complete process, flexible collocation, combined with multiple spinning methods;

  • Customizable width 1200/1600/1800mm;

  • Automatic roll-roll system; 

  • Precision liquid supply system; 

  • Controllable environmental temperature and humidity;

  • Nanofiber membrane drying post-treatment system; 

  • Security protection system;

  • Liquid supply system: Corrosion resistance, high pressure resistance.

Related link: https://www.nanofiberlabs.com/product/nano-instant-mask-production-line.html

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