Large-Scale Nanofiber Manufacturing| Thermal Transfer Printed Flexible and Wearable Bionic Skinwith Bilayer Nanofiber for Comfortable Multimodal HealthManagement

In recent years, sweat sensor technology has garnered significant attention due to its non-invasive and real-time monitoring capabilities. However, most current bionic skin technologies face multiple challenges, including complex and costly manufacturing processes, poor wearability, and difficulties in real-time health monitoring. These limitations have hindered the widespread adoption and practical application of bionic skin across various fields.

Recently, a research team led by Academician Jinlian Hu at City University of Hong Kong has developed an innovative bionic skin sweat sensor that addresses these technical shortcomings through a novel thermal transfer printing manufacturing method. This cost-effective and user-friendly approach is particularly suitable for small-scale commercial production. The team's (original) double-layer unidirectional moisture-wicking nanofiber membrane provides exceptional stretchability and breathability, enabling efficient sweat absorption and comfortable real-time health monitoring for wearers.

Notably, this sensor integrates an advanced detection system capable of monitoring multiple biomarkers in sweat, including glucose, lactate, uric acid, pH, temperature, and skin impedance. When combined with the newly developed CARE (Continuous Analyte Monitoring with Real-time Engagement) system, it achieves real-time data transmission and processing, delivering a comprehensive solution for reliable and comfortable health monitoring. These findings were published in Advanced Healthcare Materials under the title "Thermal Transfer Printed Flexible and Wearable Bionic Skin with Bilayer Nanofiber for Comfortable Multimodal Health Management."

The study details this specialized bionic skin sweat sensor that incorporates multiple electrodes for comprehensive analysis. Each electrode is crucial for providing real-time, accurate data, with experimental results demonstrating the sensor's high sensitivity and accuracy in detecting sweat parameters. The thermal transfer printing process ensures a simple, cost-effective manufacturing method ideal for small-batch sensor production. Compared to conventional methods, this thermal transfer technology enables more efficient and reliable precise arrangement of sensor components.

Additionally, the electrospun nanofiber membrane layer features unidirectional moisture transfer and excellent breathability, ensuring wearing comfort. Wearability tests confirmed the bionic skin's outstanding flexibility, breathability, and moisture permeability, allowing extended wear without discomfort. Biocompatibility tests further verified the device's safety with no skin irritation or allergic reactions.

In conclusion, this bionic skin sweat sensor represents a significant advancement in wearable health monitoring technology, opening new possibilities for medical applications, sports science, and personal health management.

图2：双层纳米膜的功能表征。

图3：汗液传感器的传感性能表征。

图4：电子皮肤汗液传感器的其他性能表征及其生物相容性测试和延展性测试。

图5：生物皮肤传感器在人体运动过程中的持续性健康监测。