Electrospinning of Nanofiber Fibrinogen Structures

Views: 715 Author: Site Editor Publish Time: 2021-03-22 Origin: Site

The first results of electrospinning fibrinogen nanofibers for use as a tissue-engineering scaffold, wound dressing, or hemostatic bandage are reported. Structures composed of fibrinogen fibers with an average diameter of 80−700 nm were electrospun from solutions composed of human or bovine fibrinogen fraction I dissolved in 1,1,1,3,3,3-hexafluoro-2-propanol and minimal essential medium (Earle's salts). In summary, the electrospinning process is a simple and efficient technique for the fabrication of 3D structures composed of fibrinogen fibers, as would be present in the physiologic environment.

Electrospinning of Nanofiber Fibrinogen Structures 

 

 

 

Published:2021

Journal:Nano Letters

Impact Factor:13.693

Paper link:https://pubs.acs.org/doi/abs/10.1021/nl025866c


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